Joe Schmidt has made 14 changes to the Ireland team that beat the All Blacks for this Saturday's game against the United States.
Only Garry Ringrose - who missed the win over Argentina - has retained his place. Cian Healy and Josh Van Der Flier are on the bench, while Joey Carbery and John Cooney start as the half-backs.
Here's the team in full:
15. Will Addison
14. Andrew Conway
13. Garry Ringrose
12. Stuart McCloskey
11. Darren Sweetnam
10. Joey Carbery
9. John Cooney
1. Dave Kilcoyne
2. Niall Scannell
3. Finlay Bealham
4. Tadhg Beirne
5. Iain Henderson
6. Rhys Ruddock (captain)
7. Jordi Murphy
8. Jack Conan.
Replacements:
16. Rob Herring
17. Cian Healy
18. John Ryan
19. Quinn Roux
20. Josh van der Flier
21. Luke McGrath
22. Ross Byrne
23. Sam Arnold